Question 1

What is TRILACICLIB used for?

Accepted Answer

TRILACICLIB (brand name COSELA) is a Other indicated for See full prescribing information.

Question 2

How does TRILACICLIB work?

Accepted Answer

TRILACICLIB works through the following mechanism: 12.1 Mechanism of Action Trilaciclib is a transient inhibitor of CDK 4 and 6. Hematopoietic stem and progenitor cells (HSPCs) in the bone marrow give rise to circulating neutrophils, RBCs, and platelets. HSPC proliferation is dependent on CDK4/6 activity..

Question 3

What are the most common side effects of TRILACICLIB?

Accepted Answer

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for TRILACICLIB. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Question 4

Is TRILACICLIB the same as COSELA?

Accepted Answer

COSELA is a brand name for TRILACICLIB. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

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