What is VENLAFAXINE HYDROCHLORIDE used for?

VENLAFAXINE HYDROCHLORIDE (brand name Venlafaxine Hydrochloride) is a SNRI indicated for See full prescribing information.

What are the most common side effects of VENLAFAXINE HYDROCHLORIDE?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for VENLAFAXINE HYDROCHLORIDE. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is VENLAFAXINE HYDROCHLORIDE the same as Venlafaxine Hydrochloride?

Venlafaxine Hydrochloride is a brand name for VENLAFAXINE HYDROCHLORIDE. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

VENLAFAXINE HYDROCHLORIDE

Q: How does VENLAFAXINE HYDROCHLORIDE work?

VENLAFAXINE HYDROCHLORIDE works through the following mechanism: 12.1 Mechanism of Action The mechanism of action of venlafaxine in the treatment of MDD, GAD, SAD, and PD is unclear, but is thought to be related to the potentiation of serotonin and norepinephrine in the central nervous system, through inhibition of their reuptake..

SNRI

Brand names: Venlafaxine Hydrochloride

Oral

Mechanism of Action

12.1 Mechanism of Action The mechanism of action of venlafaxine in the treatment of MDD, GAD, SAD, and PD is unclear, but is thought to be related to the potentiation of serotonin and norepinephrine in the central nervous system, through inhibition of their reuptake.

Indications

See full prescribing information

Contraindications

• 4 CONTRAINDICATIONS Venlafaxine hydrochloride extended-release capsules are contraindicated in patients: with known hypersensitivity to venlafaxine hydrochloride
• desvenlafaxine succinate or to any excipients in the formulation [see Adverse Reactions (6.2) ] . taking
• or within 14 days of stopping
• MAOIs (including the MAOIs linezolid and intravenous methylene blue) because of the risk of serotonin syndrome [see Dosage and Administration (2.11)
• Warnings and Precautions (5.2)

FDA Warnings

5 WARNINGS AND PRECAUTIONS Serotonin Syndrome : Increased risk when co-administered with other serotonergic agents, but also when taken alone
Increased Risk of Bleeding : Concomitant use of aspirin, NSAIDs, other antiplatelet drugs, warfarin, and other anticoagulants may increase risk ( 5
There was considerable variation in risk of suicidal thoughts and behaviors among drugs, but there was an increased risk identified in young patients for most drugs studied
There were differences in absolute risk of suicidal thoughts and behaviors across the different indications, with the highest incidence in patients with MDD

Known Side Effects

12 documented side effects by frequency

Drug Not Working

>10%

Nausea

1-10%

Fatigue

1-10%

Headache

1-10%

Dizziness

1-10%

Depression

1-10%

Anxiety

1-10%

Diarrhea

1-10%

Vomiting

1-10%

Insomnia

1-10%

Falls

1-10%

Shortness of Breath

0.1-1%

Community Discussions

No community discussions found for VENLAFAXINE HYDROCHLORIDE yet.

Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → VENLAFAXINE HYDROCHLORIDE openFDA label JSON → VENLAFAXINE HYDROCHLORIDE FAERS adverse-event reports → VENLAFAXINE HYDROCHLORIDE ClinicalTrials.gov → completed Phase 2+ trials of VENLAFAXINE HYDROCHLORIDE

Compare With

10 available comparisons

Formulations

Dosage Forms

Tablet

Route

Oral