What is VILAZODONE HYDROCHLORIDE used for?

VILAZODONE HYDROCHLORIDE (brand name VILAZODONE HYDROCHLORIDE) is a Atypical Antidepressant indicated for See full prescribing information.

What are the most common side effects of VILAZODONE HYDROCHLORIDE?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for VILAZODONE HYDROCHLORIDE. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is VILAZODONE HYDROCHLORIDE the same as VILAZODONE HYDROCHLORIDE?

VILAZODONE HYDROCHLORIDE is a brand name for VILAZODONE HYDROCHLORIDE. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

VILAZODONE HYDROCHLORIDE

Q: How does VILAZODONE HYDROCHLORIDE work?

VILAZODONE HYDROCHLORIDE works through the following mechanism: 12.1 Mechanism of Action The mechanism of action of vilazodone in the treatment of major depressive disorder is not fully understood, but is thought to be related to its enhancement of serotonergic activity in the CNS through selective inhibition of serotonin reuptake. Vilazodone is also a partial agonist at serotonergic 5-HT 1A receptors; however, the net result of this action on serotonergic transmission and its role in vilazodone’s antidepressant effect are unknown..

Atypical Antidepressant

Brand names: VILAZODONE HYDROCHLORIDE

Oral

Mechanism of Action

12.1 Mechanism of Action The mechanism of action of vilazodone in the treatment of major depressive disorder is not fully understood, but is thought to be related to its enhancement of serotonergic activity in the CNS through selective inhibition of serotonin reuptake. Vilazodone is also a partial agonist at serotonergic 5-HT 1A receptors; however, the net result of this action on serotonergic transmission and its role in vilazodone’s antidepressant effect are unknown.

Indications

See full prescribing information

Contraindications

• 4 CONTRAINDICATIONS Vilazodone hydrochloride tablets are contraindicated in: • Patients taking
• or within 14 days of stopping
• monoamine oxidase inhibitors (MAOIs)
• including MAOIs such as linezolid or intravenous methylene blue
• because of an increased risk of serotonin syndrome [see Warnings and Precautions (5.2)

FDA Warnings

5 WARNINGS AND PRECAUTIONS • Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents (e
• Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk (5
There was considerable variation in risk of suicidal thoughts and behaviors among drugs, but there was an increased risk identified in young patients for most drugs studied
There were differences in absolute risk of suicidal thoughts and behaviors across the different indications, with the highest incidence in patients with MDD

Known Side Effects

12 documented side effects by frequency

Diarrhea

1-10%

Nausea

1-10%

Anxiety

1-10%

Insomnia

1-10%

Drug Not Working

1-10%

Headache

1-10%

Depression

1-10%

Dizziness

1-10%

Fatigue

1-10%

Weight Gain

0.1-1%

Tingling/Numbness

0.1-1%

Vomiting

0.1-1%

Community Discussions

No community discussions found for VILAZODONE HYDROCHLORIDE yet.

Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → VILAZODONE HYDROCHLORIDE openFDA label JSON → VILAZODONE HYDROCHLORIDE FAERS adverse-event reports → VILAZODONE HYDROCHLORIDE ClinicalTrials.gov → completed Phase 2+ trials of VILAZODONE HYDROCHLORIDE

Compare With

7 available comparisons

Formulations

Dosage Forms

Tablet

Route

Oral