Compare EMPAGLIFLOZIN (JARDIANCE) and Lisinopril (Zestril) — clinical data, side effects, and patient experiences.
JARDIANCE, Jardiance, Synjardy · SGLT-2 Inhibitor
How it works
12.1 Mechanism of Action Empagliflozin is an inhibitor of the sodium-glucose co-transporter 2 (SGLT2), the predominant transporter responsible for reabsorption of glucose from the ...
Approved for
Zestril, Prinivil · ACE Inhibitor
How it works
Inhibits angiotensin-converting enzyme (ACE), preventing conversion of angiotensin I to angiotensin II, a potent vasoconstrictor, leading to decreased blood pressure and reduced al...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 21 Reddit discussions
EMPAGLIFLOZIN
20%
positive
15 threads
Lisinopril
67%
positive
6 threads
% of discussions mentioning each side effect
15 Reddit threads analysed for EMPAGLIFLOZIN
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
13 upvotes
Most discussed side effects in community
I have my monthly checkup soon and my lab test came (finally) under 6 after 4 months of daily exercise and low carb diet (im currently just taking 25 mg empagliflozin). So incredibly grateful for this community and working towards managing it without any medications. 🥲 I will be celebrating with
I’ve been T2 for 10+ years and I was diagnosed at a pretty young age (21), so it’s really something I’ve been living with for my whole adult life, and over that time my treatment has changed, and new medications have been added where it’s been needed to help keep my levels under control. My GP has r
**So an Update: I asked my primary care doctor that I wanted to go and see an endocrinologist. I got told that I do not qualify to see one. She claims I am a diabetic but I can't go and see a endocrinologist.** So, went to my doctor at the VA end of last month. Had blood work done. No one told me
I just read in an article that someone was paying over $500 a month for that single drug alone. How in the hell do you poor US citizens manage your healthcare costs? It's difficult for me to get my head around tbh
I was diagnosed with diabetes roughly 3 weeks ago with an HBA1c of 12 and prescribed metformin xr, empagliflozin, sitagliptin, and got a cgm as well. Changed my diet abruptly and removed all food with added sugars and bad carbs and I found out doing IF 16/8 helps as well. Also added exercise through
In the last few months, I’ve been stress-eating and fully aware that my lifestyle is incredibly unhealthy. Despite knowing better, I didn’t care so much, overwhelmed by stress from work and my personal life. As a result, I started experiencing the usual symptoms—feeling thirsty and frequently needin
The warnings for Jardiance (Empagliflozin) include this statement Jardiance may increase the risk of lower limb amputation (especially of the toe and foot). The risk is higher if you have poor blood flow in the legs, nerve problems, foot ulcers, or have had a previous amputation. To lessen the risk
I recently spent four months doing a clinical trial with Empagliflozin. This is my experience and I want as many Type I's to see it as possible. I am writing this post in order to spread the word about its effectiveness in my case. It is not currently prescribed to Type I’s because there is risk of
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
6 Reddit threads analysed for Lisinopril
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
46 upvotes
Most discussed side effects in community
I wanted to share my experience in case it helps someone who might be in the same confusing situation I was in. I’m a **46 year old male,** fairly active, healthy weight, and generally careful with my lifestyle. About a year and a half ago, I started paying closer attention to my blood pressure, whi
Just wanted to share my story of getting my BP under control as motivation for all of us who struggle with it. I am 46 yo, fit and athletic individual (155lbs, distance runner, scuba diver) who had a reasonably good diet and mild alcohol use. During a regular health checkup, my BP was very high and
I've been dealing with high blood pressure for 6-7 years now, back in 2020 it was as high as 160/110, and no meds helped me until I finally went on 40 mg of Lisinopril and 12.5 mg of HCTZ. Last year I got into a minor car accident and they incidentally found a small tumor on my left adrenal gland. T
I have had stage two hypertension for almost a decade now, at age 37. It's mostly my regular body so it hasn't been possible to reach normal levels without meds. I was on 5 mg Lisinopril and 5 mg of amlodopine for a while, but after losing weight and exercising I was able to go off amlodopine. But t
I went to the doctor today to be seen for retina problems arising from high blood pressure..but, when they took my blood pressure (I have been on beetroot for about a month now), they said my blood pressure was 100/68? I could not believe it, I thought they were going to give me lisinopril or someth
Losing hope For the sake of brevity, I’ll leave out a long story that goes with this. 35 male other wise healthy Treatment resistant hypertension with PVCs and tachycardia since 18 years of age. On 4-5 BP meds nothing really works. Renal artery scan - nothing Aldosterone abnormalities - none Adrena
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
EMPAGLIFLOZIN is a SGLT-2 Inhibitor, while Lisinopril belongs to the ACE Inhibitor class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles.
EMPAGLIFLOZIN carries 4 FDA warnings. Lisinopril carries 2 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.
Every figure on this comparison links back to its primary source. See data sources and methodology for the full provenance trail.