Compare EXENATIDE (Byetta) and TIRZEPATIDE (Zepbound) — clinical data, side effects, and patient experiences.
Byetta, Bydureon · GLP-1 Agonist
How it works
12.1 Mechanism of Action Incretins, such as glucagon-like peptide-1 (GLP-1), enhance glucose-dependent insulin secretion and exhibit other antihyperglycemic actions following their...
Approved for
Zepbound, ZEPBOUND, Zepbound KwikPen · GLP-1 / GIP Agonist
How it works
12.1 Mechanism of Action Tirzepatide is a GIP receptor and GLP-1 receptor agonist. It contains a C20 fatty diacid that enables albumin binding and prolongs the half-life. Tirzepati...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 19 Reddit discussions
EXENATIDE
29%
positive
7 threads
TIRZEPATIDE
42%
positive
12 threads
% of discussions mentioning each side effect
7 Reddit threads analysed for EXENATIDE
Overall Sentiment
Slightly positive
Comparison Threads
0
Avg Post Score
40 upvotes
Most discussed side effects in community
I'm just curious. The more I experience this pain and weakness the more I realize this is what sleep deprivation is. Without proper restorative sleep you get the exact same symptoms. Poorer sleep leads to a disruption in hormonal levels which makes sense why this affects more women then men. They
I just finished reading an *excellent* series of blog posts about how the fear of insulin is mostly bullshit. I wanted to understand the articles better, and contribute to fittit, so I went through each article and summarized them the best as I could in layman terms. All of them are worth a read, an
Since we can't submit links on this sub, I'm pasting an interesting article I saw today. It's by Sarah Zhang for the Atlantic. Did Scientists Accidentally Invent an Anti-addiction Drug? People taking Ozempic for weight loss say they have also stopped drinking, smoking, shopping, and even nail biting
Fair warning: this will be a long post filled with data and graphs and some potentially controversial commentary. You may feel the urge to express how I am doing something wrong, not eating enough, etc. I’ve seen and read it all so it will fall on deaf ears here, but have at it I suppose. I plan to
My health plan formulary updates for GLPS! As a PA tech, not looking forward to alllllll the calls and PAs we’re about to get lol -GLP medications for diabetes will require step-therapy on October 1 2023. This update applies to dulaglutide (Trulicity), exenatide (Bydureon and Byetta), liraglutide (
Invex Therapeutics # Background Invex Therapeutics is a clinical stage biopharmaceutical company incorporated on the 8th of March in 2019 which is repurposing an orphan drug (Exenatide) for initial use in the indication of Idiopathic Intracranial Hypertension (IIH). A basic understanding of the sc
Before starting I have to say that I had a BMI of 31 when starting Mounjaro and answered all the pharmacy questions completely truthfully. Also, apologies for the long post. Mounjaro is licensed for people with a BMI above 30 or above 27 with weight related health problems. However, the licence does
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
12 Reddit threads analysed for TIRZEPATIDE
Overall Sentiment
Mixed
Comparison Threads
1
Avg Post Score
15 upvotes
Most discussed side effects in community
Threads directly comparing TIRZEPATIDE to other medications
Update.. my uncontrolled T2 is now under control. I’ve decided to take Mounjaro and I no longer have crazy spikes. So far no side effects. Hey everyone! 👋 My doctor recently gave me two options to help lower my A1C—Ozempic and Mounjaro (Tirzepatide). I’d love to hear from anyone who’s taken either
Recently diagnosed type 2. Have been on metformin since December 1. Have lost about 10 pounds with it but the diarrhea is too much for my system, and i was only at 1000mg extended release once a day. Doc told me to discontinue metformin. Was then contacted by the “weight management” team. They t
It’s amazing how life can turn on a dime. Last week, I was bummed because I had a check up and expected to see improvement in my A1C (blood sugar) after 10 weeks on tirzepatide. Instead, it had shot up into diabetic range. I felt pretty overwhelmed thinking about how I was going to manage yet anothe
So I was diagnosed as diabetic at the beginning of this month. My doctor has been useless. He called me to tell me my blood work showed diabetes and to take metformin for three months and then see him again. That was it. He didn't even tell me what my a1c was or anything. He prescribed me tirzepatid
I am so frustrated! I have been on Mounjaro 12.5mg for about 18 months now, having titrated up from 10mg. I transferred to Mounjaro because Trulicity was not having the same impact as the Ozempic, which I was forced to swap to after my insurance company changed their formulary and Ozempic stopped
I just started this meditation 3 weeks ago so far so good my sugar levels are dropping and no metformin yay 😀 if I loose any weight it will be a bonus I’m currently on 2.5 has anyone dropped weight on this mg ?
Pretty much the post title. For those taking a GLP-1 medication, especially those who are well controlled, has taking a GLP-1 allowed you to feel less paranoid about what you eat? For context, Dx T2 last year with A1C of 7.1, potential LADA dx in Feb (C peptide is solidly normal). 1000mg of metformi
Like many people, the pandemic hit me hard—but not just emotionally. During lockdown, I found myself turning to food for comfort. The weight crept on until I reached 14 stone 10 lbs. At just 5'3", I felt heavy, sluggish, and uncomfortable. To put it into perspective, the last time I’d been close to
My dad is 70 and we need help. He has just about everything wrong with him, kidney disease, high blood pressure, congestive heart failure(unsure of the stage, but I would guess rather advanced, diabetes for 30 years, COPD(thankfully has stopped smoking). He's been battling this fluid build up that
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
EXENATIDE is a GLP-1 Agonist, while TIRZEPATIDE belongs to the GLP-1 / GIP Agonist class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles.
EXENATIDE carries 4 FDA warnings. TIRZEPATIDE carries 4 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.
Every figure on this comparison links back to its primary source. See data sources and methodology for the full provenance trail.