Compare GABAPENTIN (Gabapentin) and TOPIRAMATE (Topiramate) — clinical data, side effects, and patient experiences.
Gabapentin, Neurontin · Anticonvulsant
How it works
12.1 Mechanism of Action The precise mechanisms by which gabapentin produces its analgesic and antiepileptic actions are unknown. Gabapentin is structurally related to the neurotra...
Approved for
Topiramate, Topamax · Anticonvulsant
How it works
12.1 Mechanism of Action The precise mechanisms by which topiramate exerts its anticonvulsant and preventive migraine effects are unknown; however, preclinical studies have reveale...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 24 Reddit discussions
GABAPENTIN
50%
positive
10 threads
TOPIRAMATE
21%
positive
14 threads
% of discussions mentioning each side effect
10 Reddit threads analysed for GABAPENTIN
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
391 upvotes
Most discussed side effects in community
I need to feel like I’m not crazy. I was diagnosed with fibro about two years ago. Underwent quite a few tests including an EMG to rule out other things. Currently taking gabapentin to help symptoms. But along with the pain I get so many muscle twitches. Kind of like when you get that really annoyi
Today my boyfriend of a year told me he doesn’t think I should be taking my opioid pain medication any longer. I have had chronic pain for 18 years, have tried every single thing I could think of, that was recommended to me, have had multiple surgeries, and ended up with CRPS in my right hip/thigh.
I'm going to share my story and what I've found does work and doesn't work for me. Feel free to ask questions. And feel free to comment with your own journey. I was diagnosed at 23. I went to Disney world and on the second day I woke up and couldn't walk. I was in so much pain. My legs and feet wer
And the only fibromyalgia drug in existence as far as any of them know is gabapentin, but gabapentin makes it so you can't feel your clitoris.
I had my monthly appointment with my PM doc this morning. I brought up the new drug that has just been approved by the FDA and wanted to get his thoughts on it. He said and I am quoting him pretty detailed here; The drug has only been approved by the FDA for acute pain only, as in post surgical pa
I work in a pharmacy, which is honestly an awful environment if you have chronic pain and fatigue because I'm absolutely killed after every shift, but honestly it's the attitudes of my coworkers that really cut deep. Right now, I'm not taking any opioid medication, but I did in the past and it's rea
So over 3 years ago now I had a very unpleasant situation occur with my pain doctor at the time. (The link to that long story is here: [https://www.reddit.com/r/ChronicPain/comments/xq86rj/an\_update\_to\_an\_arrogant\_doctor\_forcing\_me\_to\_go/](https://www.reddit.com/r/ChronicPain/comments/xq86r
I was hit by a fckn truck. I’m being as positive as I can be. She went on to say that she got better from her accident using positive thoughts and yoga. I wish I could do yoga. I’m in physical therapy with a goal of hopefully being able to do yoga again one day. No essential oil ointments don’t help
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
14 Reddit threads analysed for TOPIRAMATE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
16 upvotes
Most discussed side effects in community
# General Info An Anticonvulsant may be used as a mood stabilizer to treat mood disorders characterized by intense and sustained mood shifts, typically Bipolar Disorder. Mood stabilizers suppress swings between mania and depression. The oldest and most studied mood stabilizer is [Lithium](https://ww
Hi all, I know this is a common question/topic of discussion here but I’m so frustrated and I’m looking for any help. I’m currently on 1200 lithium and 150 lamictal. Started 50 topiramate once a night 3 1/2 weeks ago, have seen no results, no change in appetite, nothing. I was diagnosed a year ago
So my husband turned 28 today. It's his first birthday since we got married, his first birthday in years when all our friends can hang out, he has the day off, we have our own place, and generally everything is good. Only problem is that this morning I woke up with my mania coming to a screeching ha
Hi everyone, if you’re reading this, thank you. From the deepest I can, I appreciate you. I ***finally*** got my diagnosis on the 30th of September after many years of confusion, seeing multiple counselors, therapists, doctors and psychiatrists. Earlier in the month I voluntarily spent a week in th
Hey all! I started noticing significant shedding of my hair about six months after upping my dose of topiramate to 75 mg/day. It seemed to get worse when I switched generic brands to Teva and right now about 2/3 of my hair is gone. Literally clumps were falling out on my floors and I was cleaning
It’s a mixture of bad choices influenced by a depression episode and reasons out of my control. I was fit last summer during a hypomanic episode then I went through a following depression episode last fall/winter and gained 30lb through binge eating. Hovered there. Then got meds adjusted to change t
As of late I have found it very hard to get out of the house. I can get up, shower, eat but when it finally comes time to leave; I just can’t. Going to the store is no problem, but getting out to go do something is seemingly impossible. I’ve recently went under some pretty drastic medication changes
I was prescribed it in the hospital because they didn’t think I was taking the lithium even though I was and they thought I was allergic to lamictal even though I’m not, and I refuse to take depakote, so they went with topamax, but I don’t hear of anyone taking topamax as a mood stabilizer. Everyone
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
Both GABAPENTIN and TOPIRAMATE belong to the Anticonvulsant class. While they share a similar mechanism of action, differences in pharmacokinetics, dosing, and side effect profiles may make one more suitable than the other for individual patients.
GABAPENTIN carries 4 FDA warnings. TOPIRAMATE carries 4 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.
Every figure on this comparison links back to its primary source. See data sources and methodology for the full provenance trail.