Compare LAMOTRIGINE (Lamotrigine) and LEVETIRACETAM (Levetiracetam) — clinical data, side effects, and patient experiences.
Lamotrigine, Lamictal · Anticonvulsant
How it works
12.1 Mechanism of Action The precise mechanism(s) by which lamotrigine exerts its anticonvulsant action are unknown. In animal models designed to detect anticonvulsant activity, la...
Approved for
Levetiracetam, Keppra · Anticonvulsant
How it works
12.1 Mechanism of Action The precise mechanism(s) by which levetiracetam exerts its antiepileptic effect is unknown. A saturable and stereoselective neuronal binding site in rat br...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 24 Reddit discussions
LAMOTRIGINE
22%
positive
9 threads
LEVETIRACETAM
13%
positive
15 threads
% of discussions mentioning each side effect
9 Reddit threads analysed for LAMOTRIGINE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
121 upvotes
Most discussed side effects in community
I’m a writer. Maybe not a successful one at this point in my life, but it’s what I identify as. Writing has been such a big part of my life for as long as I can remember. Writing is one of the few things I am confident I can do, regardless of my mental state, and it has been my personal therapy for
Edit: I just got on new medication last week. I’m not looking to get attention I’m truly asking for help. I also just went through an episode of hitting myself. Which truly felt like it helped to let that out. I know that sounds terrible but I feel better now. I feel bad that my dog just saw me do a
soooo i just recently (in this last month) got diagnosed bcos i felt myself completely slipping. i sought out a doctor, homie did an evaluation and prescribed me meds. i was very unsure as far as whether he was correct abt the diagnosis or not so i went in for a second opinion and sure as hell, “you
I went to the eye doctor yesterday and when she saw i was lamotrigine i clarified i didn't have epilepsy but bipolar and she went on a rant about how i should get a second job because if i'm busy i wont have time to be mentally ill. like the whole appointment. girl i just wanted some new glasses. i
I was recently diagnosed with bipolar 1 about a month ago and I’ve been taking 200mg of Lamotrigine and 45 mg of latuda. My family is very VERY religious and they want me to go to a special priest hoping that I get cured of being bipolar. I know doing this will not bring me any harm, but I generally
Recently i had to find a new psychiatrist because my insurance changed. I told him I’ve been on lithium and lamotrigine for several years and he told me that he used to work at an inpatient facility and he’d only ever used lithium with those patients and would wean them off after they left. He sugge
Ok so first things first, the medicine works great for me. My complaint is the pill itself. Whoever designed them is the spawn of fucking satan and deserves the most awful of punishments. It’s just compressed powder. It dissolves in water, which is what spit is. Like who the fuck approved this shit.
Called the pharmacy Thursday to refill my prescriptions as usual, knowing I had at least one refill left, which would have gotten me through til my psych gets back July 4th. Pharmacist said it would be ready by 9am today (Saturday) because they didn't have the right size pills for my lamotrigine and
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
15 Reddit threads analysed for LEVETIRACETAM
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
101 upvotes
Most discussed side effects in community
Hi all, I’m a patient at one of the top migraine centers in the country (Diamond Headache Clinic in Chicago). They do a lot of off-label/ non-conventional treatments, so I feel like I have a pretty good list of known treatments. Feel free to add to it in the comments. Hope this helps someone!! THIS
I finally broke down and got these TimerCap caps from Amazon. I am really good about taking my meds usually, but I have been really sick this week and actually double dosed on accident. I can't stand those pill organizers, so I'm going to give these a shot. I attached photos so you can see that the
I hope the streak continues. I was diagnosed 3 years ago with Left TLE. I was having 2 grand Mal a month at the beginning and while they tweaked my meds it started varying. I’m on 2 meds (Levetiracetam, Oxcarbazepine) now and for the last year nothing has happened. Just this week for the first time
People seem to really dislike levetiracetam here. For me it’s been great. No side effects at all, if you don’t count that it totally took away my motion sickness, which I had even before epilepsy. Fingers crossed for another six months and I’ll get my drivers license back!
While other drugs clear existing plaques, levetiracetam (keppra) prevents production of toxic amyloid beta peptides https://news.northwestern.edu/stories/2026/02/common-anti-seizure-drug-prevents-alzheimers-plaques-from-forming I take Keppra. It keeps the seizures at bay, but it also makes me drowsy
I am angry, I can’t remember anything literally 2 seconds later, I can’t talk properly, I keep stuttering, I have ZERO thoughts ZERO. empty brain. it’s managing my seizures, but I don’t like how im feeling on it at all. Did you guys switch from it one that managed your seizures and wasn’t as enragi
(18F) I’m just wondering if anyone has any experiences similar to what I’m going through. I have complex partial seizures. The cause of these seizures is heterotopia in my brain. I have been taking keppra/levetiracetam for around 6 months now. It isn’t perfect but has made massive improvements. I’m
I take 1000 mg of Keppra/Levetiracetam and 400 Lamictal/Lamotrigine. And I am so fucking tired all the time. There isn't a moment of my day that I couldn't lay down and just, fall asleep. My memory is bad enough that I'll forget what I was gonna say in the middle of saying it, or forget what someone
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
Both LAMOTRIGINE and LEVETIRACETAM belong to the Anticonvulsant class. While they share a similar mechanism of action, differences in pharmacokinetics, dosing, and side effect profiles may make one more suitable than the other for individual patients.
LAMOTRIGINE carries 4 FDA warnings. LEVETIRACETAM carries 4 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.
Every figure on this comparison links back to its primary source. See data sources and methodology for the full provenance trail.