Compare Lisinopril (Zestril) and METOPROLOL (METOPROLOL TARTRATE) — clinical data, side effects, and patient experiences.
Zestril, Prinivil · ACE Inhibitor
How it works
Inhibits angiotensin-converting enzyme (ACE), preventing conversion of angiotensin I to angiotensin II, a potent vasoconstrictor, leading to decreased blood pressure and reduced al...
Approved for
METOPROLOL TARTRATE, Lopressor, Toprol-XL · Other
How it works
12.1 Mechanism of Action Metoprolol is a beta 1 -selective (cardioselective) adrenergic receptor blocking agent. This preferential effect is not absolute, however, and at higher pl...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 19 Reddit discussions
Lisinopril
67%
positive
6 threads
METOPROLOL
38%
positive
13 threads
% of discussions mentioning each side effect
6 Reddit threads analysed for Lisinopril
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
46 upvotes
Most discussed side effects in community
I wanted to share my experience in case it helps someone who might be in the same confusing situation I was in. I’m a **46 year old male,** fairly active, healthy weight, and generally careful with my lifestyle. About a year and a half ago, I started paying closer attention to my blood pressure, whi
Just wanted to share my story of getting my BP under control as motivation for all of us who struggle with it. I am 46 yo, fit and athletic individual (155lbs, distance runner, scuba diver) who had a reasonably good diet and mild alcohol use. During a regular health checkup, my BP was very high and
I've been dealing with high blood pressure for 6-7 years now, back in 2020 it was as high as 160/110, and no meds helped me until I finally went on 40 mg of Lisinopril and 12.5 mg of HCTZ. Last year I got into a minor car accident and they incidentally found a small tumor on my left adrenal gland. T
I have had stage two hypertension for almost a decade now, at age 37. It's mostly my regular body so it hasn't been possible to reach normal levels without meds. I was on 5 mg Lisinopril and 5 mg of amlodopine for a while, but after losing weight and exercising I was able to go off amlodopine. But t
I went to the doctor today to be seen for retina problems arising from high blood pressure..but, when they took my blood pressure (I have been on beetroot for about a month now), they said my blood pressure was 100/68? I could not believe it, I thought they were going to give me lisinopril or someth
Losing hope For the sake of brevity, I’ll leave out a long story that goes with this. 35 male other wise healthy Treatment resistant hypertension with PVCs and tachycardia since 18 years of age. On 4-5 BP meds nothing really works. Renal artery scan - nothing Aldosterone abnormalities - none Adrena
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
13 Reddit threads analysed for METOPROLOL
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
19 upvotes
Most discussed side effects in community
Male , 26. So I had a bit of a shock yesterday. Went to the doctor for a regular check, they took my BP three times within a few minutes: 153/100 165/103 145/95 The doctor immediately prescribed me 25 mg metoprolol. But here’s the confusing part — at home I’ve been checking for the past 1.5 years, a
I have been working on my hypertension since 2019 when at a company health check my BP was 170/110. I am on metoprolol and htcz. I white coat quite badly but I'm working on that. Today at the office reading came in 115/70. Felt good to find the right doses.
I’ve had hypertension since my early 20’s and was initially prescribed lisinopril and later perindopril (both ace inhibitors) to control it. My numbers were usually “ok” with those meds, but unfortunately I developed the ace inhibitor cough and asked my doctors about alternatives. He originally pu
My last few doctors appts I’ve had high blood pressure and I chalked it up to white coat hypertension. And then it happened again so I opted to start tracking at home. Unfortunately it was high at home. I am overweight (I need to lose about 70lbs), but I’m only 32. I also have HORRIBLE anxiety abou
Quick background: For the last several years, I (33m, 6'2", 235 lbs) had been on different combinations of lisinopril (with and without HCTZ), amlodipine, and metoprolol and my pressure was generally in the 140 - 150 / 100 - 110 range. Couple months ago, I went to a new doctor (old doc moved away) a
**Okay, there absolutely has to be a link of anxiety caused by blood pressure medication** *Please put your thoughts in the comments, stories, experiences, and any information you know that could add to this* 20M || Zero Anxiety Prior || Currently Taking Amlodipine 5MG || Prozac 10MG For Anxiety S
I’ve told my friends and my partner and they understand a little but I just wanted to share with some people who have had similar experiences. I’m 33 and have had blood pressure problems stemming from a shitty diet and alcoholism. Despite that, I somehow have managed to stay an ok weight at 200lbs,
Hi everyone! So this is more of a venting post. I’ve had high bp since I was about 22/23 when I was pregnant with my first son (I’m 36 now) so quite a while. It runs pretty deep on my dad’s side, so yea, here we are. Anyway, my bp has been pretty difficult to manage since my last pregnancy (2020) an
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
Lisinopril is a ACE Inhibitor, while METOPROLOL belongs to the Other class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles.
Lisinopril carries 2 FDA warnings. METOPROLOL carries 4 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.
Every figure on this comparison links back to its primary source. See data sources and methodology for the full provenance trail.