Compare AMLODIPINE (amlodipine) and Losartan (Cozaar) — clinical data, side effects, and patient experiences.
amlodipine, Norvasc, Exforge HCT · ARB
How it works
12.1 Mechanism of Action The active ingredients of amlodipine, valsartan and hydrochlorothiazide tablets target 3 separate mechanisms involved in blood pressure regulation. Specifi...
Approved for
Cozaar · ARB (Angiotensin II Receptor Blocker)
How it works
Selectively blocks the binding of angiotensin II to the AT1 receptor found in many tissues, reducing vasoconstriction, aldosterone secretion, and sympathetic activity.
Approved for
Estimated frequency (%) based on clinical trial data
Based on 15 Reddit discussions
AMLODIPINE
40%
positive
5 threads
Losartan
10%
positive
10 threads
% of discussions mentioning each side effect
5 Reddit threads analysed for AMLODIPINE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
53 upvotes
Most discussed side effects in community
35 male with high BP my entire life Been on it for 1 year and 5 months. Started at 5 mg for like 3 or 6 months then went to 10 mg. Seems I have a barrage of symptoms I’ve never had before in my life for the last 6 months. Extreme daytime sleepiness***** The chills like 15 times a day ***** Swollen
I was hungover, ate prosciutto, hands were shaking like crazy. I thought I'd measure it just for the fun of it. It wasn't fun when the numbers never in 10 measurement went lower than 210/120, going to the ER made things worse. It was all in my head. But we fixed it. Hell started. 2 months passed and
Just wanted to brag on myself a bit here. Since February I've been taking GLP-1 and I'm down 45lbs (247-202). My GW is 170 so I still have a ways to go but recently I've been having weird dizzy spells when bending down and standing back up. There are a lot of potential causes of course, but my BP ha
So I do not know exactly where to start, this whole process seems to me like an XXL episode of Dr. House with no end. So it all started with a head pressure about 3 weeks ago, I dont know exactly how to describe this I would not say that its a headache, much more like air is building up in my bra
Just found out that my father’s CAC score is 8000+. Cholesterol is 169. The score shocked me and I don’t know what to do. He’s scheduled for angiography in 1 week. I am concerned whether something could happen in 1 week… I live in another country and can’t get to him (no visa). He was told to take a
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
10 Reddit threads analysed for Losartan
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
51 upvotes
Most discussed side effects in community
Today went to see my cardiologist and no longer need to take losartan nor atorvastatin ! Got to a healthy weight and good diet that he said I no longer need the medication. Hopefully I can stay off it from now on. Im 5,8 went from 225lbs down to 185, eating a lot of food with high sodium to no/low
Hi, how is it going. Today I'm officially off blood pressure meds completely. With lifestyle changes, low sodium diet, low sugar, aerobic exercise and weight loss. I had blood pressure in the 170 to 180 systolic in January of 2025 after heart surgery on November 2024. I was 230 pounds and am current
I take 100 mg of Losartan daily, but before meds I was easily in the 140-150/90-100 range. Even after taking medication I was usually in the 130/90+ range. My resting heart rate used to sit at about 110 too. I felt like shit and my bod was so tense. But recently I stopped drinking and smoking and be
My blood pressure (seemingly) started giving me problems beginning of this year and I was put on losartan 50mg. I take that once a day and it seems to control my BP well (below 130/80). However, in the 4 months I've been on this medication, I've noticed when I'm on my period, my blood pressure shoot
Just felt compelled to write my positive experience with amlodipine. I've had high blood pressure for about 3-4 years. Average wasn't anything crazy, but around 150-160/90. I was prescribed 50 mg if Losartan, which seemed to do nothing. But I've been in it for the last 2 years. Finally, I decided Lo
I am a 35 year old male, recently diagnosed with stage 1 borderline stage 2 hypertension, my doc started me on 50 mg Losartan right away. I have a history of depression and anxiety and have tried Celexa, Lexapro, before finally settling in on Wellbutrin for a few years now, which has kept my normal
25m. I visited the doctor 2 months ago and was diagnosed with high bp and was put on 50mg Losartan. Was usually in the 150s/90 for the first week then it slowly worked but after my monthly visit back my doctor didn’t like the numbers so my dosage was doubled to 100mg. After 1 and a half months of lo
26m, started losartan in February and up until about 2 months ago it’s been goin great. I was exercising and eating right and doing everything i could to keep bp stead around the 120/80, when i last checked my bp about 2 months ago it was in that range.. These past 2 months I’ve been going through a
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
AMLODIPINE is a ARB, while Losartan belongs to the ARB (Angiotensin II Receptor Blocker) class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles.
AMLODIPINE carries 4 FDA warnings. Losartan carries 1 FDA warning. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.
Every figure on this comparison links back to its primary source. See data sources and methodology for the full provenance trail.